Publications
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Eghbali M., Curmi J.P., Birnir B., & Gage P.W. (1997). Hippocampal GABAA channel conductance increased by diazepam. Nature 388, 71-75.
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Eghbali M., Gage P.W. & Birnir B. (2000). Pentobarbital modulates g-aminobutyric acid-activated single- channel conductance in rat cultured hippocampal neurons. Mol. Pharmacol 58:463-469.
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Birnir B., Eghbali M., Everitt A.B. & Gage P.W. (2000). Bicuculline, pentobarbital and diazepam modulate spontaneous GABAA channels in rat hippocampal neurons, British Journal of Pharmacology 131: 695-704.
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Birnir B., Eghbali M., Cox G.B. & Gage P.W. (2001). GABA concentration sets the conductance of delayed GABAA channels in outside-out patches from rat hippocampal neurons. Journal of membrane biology 181:171-183.
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Zarei M.M., Zhu N., Alioua A., Eghbali M., Stefani E. & Toro L (2001). A novel MaxiK splice varient exhibits dominant negative properties. Journal of Biological Chemistry 276:16232-16239.
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Song M., Helguera G., Eghbali M., Zhu N., Zarei M. M., Olcese R., Toro L. & Stefani E (2001). Remodeling of kv4.3 potassium channel gene expression under the control of sex hormones. Journal of Biological Chemistry 276:31883-90. In this paper Song, Helguera and Eghbali equally participated.
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Eghbali M., Olcese R., Zarei M.M., Toro L. & Stefani E. (2002). External pore collapse as an inactivation mechanism for kv4.3 k+ channels. Journal of Membrane Biology 188:73-86.
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Eghbali M., Gage P.W. & Birnir B. (2003). Effects of propofol on GABA(A) channel conductance in rat- cultured hippocampal neurons. Eur J Pharmacol. 468:75-82.
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Eghbali M., Birnir B & Gage P.W. (2003). Conductance of GABAA channels activated by pentobarbitone in hippocampal neurons from newborn rats. Journal of Physiology. 552:13-22.
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Eghbali M., Toro L. & Stefani E. (2003). Diminished surface clustering and increased perinuclear accumulation of large conductance Ca2+-activated K+ channel in mouse myometrium with pregnancy. Journal of Biological Chemistry 278: 45311-7.
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Nishimaru K., Eghbali M., Stefani E. & Toro L.(2004). Function and clustered expression of MaxiK channels in cerebral myocytes remain intact with aging. Exp Gerontol. 39:831-839.
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Zarei M.M., Eghbali M., Alioua A., Song M., Knaus H.G., Stefani E., Toro L. (2004). An endoplasmic reticulum trafficking signal prevents surface expression of a voltage- and Ca2+-activated K+ channel splice variant. Proc Natl Acad Sci U S A. 101:10072-10076. In this paper Zarei, Eghbali and Alioua equally participated.
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Nishimaru K., Eghbali M., Lu R., Marijic J., Stefani E. & Toro L. (2004). Functional and molecular evidence of MaxiK channel β1subunit decrease with coronary artery ageing in the rat. Journal of Physiology 559: 849–862.
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Stefani E, Eghbali M., Minosyan TY, Alioua A & Toro L. (2004). Molecular studies in heart hypertrophy during pregnancy. J. Muscle Res Cell Motil. 25: 607.
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Eghbali M., Deva R, Alioua A, Minosyan TY, Ruan H, Wang Y, Toro L, Stefani E. (2005). Molecular and functional signature of heart hypertrophy during pregnancy. Circulation Research. 96:1208-16. Journal Cover.
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Zhu N, Eghbali M., Helguera G, Song M, Stefani E, Toro L. (2005). Alternative splicing of Slo channel gene programmed by estrogen, progesterone and pregnancy. FEBS Letter. 579: 4856-60.
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Tanaka Y., Tang G., Takizawa K., Otsuka K., Eghbali M., Song M., Nishimaru K., Shigenobu K., Koike K., Stefani E. & Toro L (2006). Kv channels contribute to NO- and ANP-induced relaxation of a rat conduit artery. J Pharmacol Exp Ther. 317:341-54.
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Ropero A.B., Eghbali M., Toro L.& Stefani E. (2006). Heart Estrogen Receptor Alpha: Distinct Membrane and Nuclear Distribution Patterns and Regulation by Estrogen. J. Mol. Cell Cardiol. 41:496- 510.
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Lu R. , Alioua A. , Kumar Y., Eghbali M., Stefani E.,&Toro L. (2006). MaxiK channel partners: physiological impact. J Physiol 570: 65–72. Journal Cover.
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Eghbali M., Wang Y., Toro L. & Stefani E. (2006). Heart Hypertrophy during pregnancy: a better functioning heart? Trends in Cardiovascular Medicine. 16:285-291.
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Cavalli A., Eghbali M., Minosyan T.Y., Stefani E.& Philipson K. (2007). Localization of sarcolemmal proteins to lipid rafts in myocardium. Cell Calcium. 42:313-22.
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Minosyan T., Lu R., Eghbali M., Toro L. & Stefani E. (2007). Increased 5-HT contractile response in late pregnant rat myometrium associates with a higher density of 5-HT2A receptors. J Physiol. 581:91- 7.
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Alioua, A., Lu R., Kumar Y., Eghbali, M., Kundu P., Toro L. & Stefani, E. (2008). Slo1 caveolin-binding motif, a mechanism of caveolin-1-Slo1 interaction regulating Slo1 surface expression. Journal of Biological Chemistry. 2008;283:4808-17.
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Lu R., Alioua A., Kumar Y., Kundu P., Eghbali M., Noelia V. Weisstaub NV, Gingrich JA, Stefani E. and Toro L (2008). 5-HT2A receptor and c-Src tyrosine kinase are closely associated supporting a tight functional coupling in rat aorta. J Physiol. 586:3855-69.
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Gomes P., Saito T., Corsso C.D., Alioua A, Eghbali M., Ligia Toro L. & Stefani E. (2008). Identification of a functional interaction between Kv4.3 channels and c-Src tyrosine kinase. Biochim. Biophys. Acta. 1783(10):1884-92.
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Kundu P., Ciobotaru A., Foroughi S., Toro L. and Eghbali M. (2008). Estrogen stimulation of KCNE2 (MiRP1) promoter activity by a direct genomic mechanism. Mol. Cell Endocrinol. 292:50-62.
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Gomes A.V., Young G.W., Wang Y., Zong C., Eghbali M., Drews O., Lu H., Stefani E.& Ping P. (2008). Contrasting proteome biology and functional heterogeneity of the 20S proteasome complexes in mammalian tissues. Mol Cell Proteomics. 8(2):302-15.
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Helguera H., Eghbali M., Sforza D., Toro L. & Stefani E. (2009). Changes in global gene expression in rat myometrium in the transition from late pregnancy to parturition. Physiological Genomics, 36(2):89- 97. In this paper Helguera and Eghbali equally participated.
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Vlashi E., Kim K., Lagadec C., Della Donna L., McDonald J.T., Eghbali M., Sayre J. W., Stefani E., McBride W.& Pajonk F. (2009). In-vivo imaging, tracking, and targeting of cancer stem cells. Journal of National Cancer Institute. 101(5):350-9.
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Saito T., Ciobotaru A., Bopassa J.C., Toro L., Stefani E. & Eghbali M. (2009). Estrogen Contributes to Gender Differences in Mouse Ventricular Repolarization. Circulation Research. 105:343-352.
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Bopassa J.C., Eghbali M., Toro L. & Stefani E. (2010). A novel estrogen receptor GPER inhibits mitochondria permeability transition pore opening and protects the heart against ischemia/reperfusion injury. Am J Physiol Heart Circ Physiol. 298(1):H16-23.
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Wu Y., Eghbali M., Ou J., Lu R., Toro L. & Stefani E. (2010). Quantitative Determination of Spatial Protein-protein Proximity in Fluorescence Confocal Microscopy. Biophys J. 98(3):493-504.
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Rahman S., Li J., Bopassa J.C., Umar S, Iorga A., Partownavid P, Eghbali M. (2011). Anesthesiology. 2011 Aug;115(2):242-53. PMCID:3322241. Accompanied by an editorial view and news release. http://newsroom.ucla.edu/portal/ucla/ucla-study-shows-good-fats-may- 211515.aspx?link_page_rss=211515
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Umar S., Nadadur R.D., Li J., Maltese F., Partownavid P., van der Laarse A & Eghbali M. (2011). Intralipid Prevents and Rescues Fatal Pulmonary Arterial Hypertension and Right Ventricular Failure in Rats. Hypertension;58(3):512-8. PMCID: 3339261.
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Umar S., Iorga A., Matori H., Nadadur R.D., Li J., Maltese F. & Eghbali M. (2011). Estrogen rescues severe pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine;184: 715-723. Journal Cover. Accompanied by an editorial view and news release. http://newsroom.ucla.edu/portal/ucla/estrogen-treatment-may-help-reverse-215186.aspx
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Umar S., Lee J. H., Lange E, Iorga A., Partow-Navid R., Bapat A., van der Laarse A., Saggar R., Saggar R., Ypey D.L., Karagueuzian H.S. & Eghbali M. (2012). Spontaneous Ventricular Fibrillation in Right Ventricular Failure Secondary to Chronic Pulmonary Hypertension. Circulation: Arrhythmia and Electrophysiology 5:181-90. PMCID: 3319685.
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Partownavid P., Umar S., Li J., Rahman S. & Eghbali M. (2012). Rescue of Bupivacaine Induced Cardiotoxicity is Abolished by Fatty Acid Oxidation Inhibitor CVT-4325. Critical Care Medicine; 40(8):2431-7.PMID: 22647409. Accompanied by an Editorial View.
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Li J., Umar S. Iorga A., Youn J.Y., Wang Y., Regitz-Zagrosek V., Cai H. & Eghbali M. (2012). Cardiac Vulnerability to Ischemia/Reperfusion Injury Drastically Increases in Late Pregnancy. Basic Research in Cardiology;107(4):271. PMID:22648276. Accompanied by a news release. http://newsroom.ucla.edu/portal/ucla/ucla-study-demonstrates-cardiac-235535.aspx.
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Matori H., Umar S., Nadadur R.D., Sharma S., Partow-Navid R., Afkhami M., Amjedi M. & Eghbali M. (2012). Genistein, a soy phytoestrogen, reverses severe pulmonary hypertension and prevents right heart failure in rats. Hypertension.; 60(2):425-30. PMCID: 4252152
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Nadadur R.D., Umar S., Iorga A., Matori H., Partow-Navid R. & Eghbali M. (2012). Reverse Right Ventricular Structural and Extracellular Matrix Remodeling by Estrogen Therapy in a Rat Model of Right Ventricular Failure. The Journal of Applied Physiology;113(1):149-58. PMCID: 3404831.
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Li J., Iorga A., Sharma S., Youn J.Y., Partow-Navid R., Umar S., Cai H. Rahman S., & Eghbali M. (2012). Intralipid, a Clinically Safe Compound, Protects the Heart Against Ischemia Reperfusion Injury more Efficiently than Cyclosporine-A. Anesthesiology;117(4):836-46. PMCID: 3769111.
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Umar S., Nadadur R.D., Iorga A., Amjedi M., Matori H. & Eghbali M. (2012). Cardiac Structural and Hemodynamic Changes Associated with Physiologic Heart Hypertrophy of Pregnancy are Reversed Postpartum. The Journal of Applied Physiology;113(8):1253-9. PMCID: 3472485
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Umar S., Rabinovitch M. & Eghbali M. (2012). Estrogen Paradox in Pulmonary Hypertension: Current Controversies and Future Perspectives. American Journal of Respiratory and Critical Care Medicine;186(2):125-31. PMCID: 3406082
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Li J., Umar S., Amjedi M., Iorga A., Sharma S., Nadadur R.D., Regitz-Zagrosek V. & Eghbali M. (2012). New Frontiers in Heart Hypertrophy during Pregnancy. American Journal of Cardiovascular Disease. 2(3):192-207. PMCID: 3427979
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Iorga A., Dewey S., Partow-Navid R., Gomes A.V. & Eghbali M. (2012). Pregnancy Is Associated with Decreased Cardiac Proteasome Activity and Oxidative Stress in Mice. PLoS ONE; 2012;7(11):e48601. doi: 10.1371/journal.pone.0048601. PMCID: 3499532
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Li J., Bopassa J.C., Rahman S. & Eghbali M (2013). In Reply:Intralipid-The New Magic Bullet in Cardioprotection? Anesthesiology;118(5):1238-40. PMID: 23612141.
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Li J., Bopassa J.C., Rahman S. & Eghbali M (2013). Inotropic effect of lipid emulsion: a new perspective. Crit Care Med;41(8):2060-2061. PMID: 23863251.
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Sharma S. & Eghbali M (2014). Influence of sex differences on microRNA gene regulation in disease. Biol Sex Differ;5(1):3. Doi: 10.1186/2042-6410-5-3. PMCID: 3912347.
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Li J., Chen X., McClusky R., Ruiz-Sundstrom M., Itoh Y., Umar S., Arnold A.P. & Eghbali M. (2014). The number of X chromosomes influences protection from cardiac ischaemia/reperfusion injury in mice: one X is better than two. Cardiovasc Res;102(3):375-84. PMCID: 4030514
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Sharma S., Umar S., Potus F., Iorga A., Wong G., Meriwether D., Breuils-Bonnet S., Mai D., Navab K., Ross D., Navab M., Provencher S., Fogelman A.M., Bonnet S., Reddy S.T. & Eghbali M. (2014). ApoA-I Mimetic Peptide 4F Rescues Pulmonary Hypertension by Inducing MicroRNA-193-3p. Circulation. 130(9):776-85. PMCID: 4194270. Accompanied by news release. http://newsroom.ucla.edu/releases/protein-in-good-cholesterol-may-be-a-key-to-treating-pulmonary- hypertension .
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Partownavid P., Sharma S., Li J., Umar S., Rahman S. & Eghbali M. (2015). Involvement of Opioid Receptors in the Lipid Rescue of Bupivacaine-Induced Cardiotoxicity. Anesth Analg;121(2):340-7. PMID: 25993392.
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Ross D., Hough G, Hama S, Aboulhosn J., Saggar R., Van Lenten B.J., Ardehali A., Eghbali M., Reddy S.T., Navab M. & Fogelman A.M. (2015). Pro-inflammatory HDL results from Oxidized Lipid Mediators in the Pathogenesis of both Idiopathic and Associated types of Pulmonary Arterial Hypertension. Pulm Circ;5(4):640-8. PMCID: PMC4671738
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Sharma S, Umar S, Centala A, Eghbali M. (2015). Role of miR206 in Genistein-Induced Rescue of Pulmonary Hypertension in Monocrotaline Model. J Appl Physiol;119(12):1374-82.PMCID: PMC4683348.
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Iorga A, Li J, Sharma S, Umar S, Bopassa JC, Nadadur RD, Centala A, Ren S, Saito T, Toro L, Wang Y, Stefani E & Eghbali M (2016). Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy. J Am Heart Assoc;5(1). pii: e002482. doi: 10.1161/JAHA.115.002482. PMCID:4859364
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Arnold AP, Reue K, Eghbali M, Vilain E, Chen X, Ghahramani N, Itoh Y, Li J, Link JC, Ngun T, & Shayna Williams-Burris S (2016).The importance of having two X chromosomes. Philos Trans R Soc Lond B Biol Sci;371(1688):20150113. doi: 10.1098/rstb.2015.0113.PMCID:4785899
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Anwar A., Ruffenach G., Mahajan A., Eghbali M. & Umar S. (2016). Novel Biomarkers for Pulmonary Arterial Hypertension. Respir Res;17(1):88. doi: 10.1186/s12931-016-0396-6. PMID: 27439993.
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Sharma S., Ruffenach G., Umar S., Motayaghani N, Reddy S.T. & Eghbali M. (2016). Role of Oxidized lipids in Pulmonary Arterial hypertension. Pulm Circ;6(3):261-73. doi: 10.1086/687293. PMID: 27683603
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Li J., Ruffenach G., Kararigas G., Cunningham C.M., Motayagheni N., Barakai N., Regitz-Zagrosek V. & Eghbali M. (2017). Intralipid protects the heart in late pregnancy against ischemia/reperfusion injury via Caveolin2/STAT3/GSK-3β pathway. J Mol Cell Cardiol;102:108-116. PMID: 27847332
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59. Arnold A.P, Cassis L.A., Eghbali M., Reue K. & Sandberg K. (2017). Sex hormones and sex chromosomes cause sex differences in the development of cardiovascular diseases. Arteriosclerosis, Thrombosis, and Vascular Biology;37(5):746-756. PMCID:5437981.
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Umar S., Partow-Navid R., Ruffenach G., Iorga A., Moazeni S. & Eghbali M. (2017). Severe Pulmonary Hypertension in Aging Female Apolipoprotein E Deficient Mice is Rescued by Estrogen Replacement Therapy. Biol Sex Differ;8:9. doi: 10.1186/s13293-017-0129-7. eCollection 2017. PMCID:5360087.
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Vaidya B., Pangallo M., Ruffenach G., Cunningham C.M., Perron J.C., Kolluru S., Eghbali M. & Gupta V. (2017). Advances in treatment of pulmonary arterial hypertension: patent review. Expert Opin Ther Pat; 11:1-12. doi: 10.1080/13543776.2017.1313232. PMID: 28355094.
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Touma M., Kang X., Gao F., Zhao Y., Cass A.A., Biniwale R., Xiao X., Eghbali M., Coppola G., Reemtsen B., & Wang Y. (2017). Wnt11 regulates cardiac chamber development and disease during perinatal maturation. JCI Insight:2(17). pii: 94904. doi: 10.1172/jci.insight.94904. PMC5621892.
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Vaillancourt M., Chia P., Sarji S., Nguyen J., Hoftman N., Ruffenach G., Eghbali M., Mahajan A. & Umar S. (2017). Autonomic Nervous System Involvement in Pulmonary Arterial Hypertension. Respir Res:18(1):201. doi: 10.1186/s12931-017-0679-6. PMCID: PMC5715548.
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Iorga A., Cunningham C.M., Moazeni S, Ruffench G, Umar S. & Eghbali M. (2017). The Protective Role of Estrogen and Estrogen Receptors in Cardiovascular Disease and the Controversial Use of Estrogen Therapy. Biol Sex Differ:8(1):33. doi: 10.1186/s13293-017-0152-8. PMID: 29065927.
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Umar S., Li J., Hannabass K., Vaillancourt M., Cunningham CM, Moazeni S. Mahajan A, & Eghbali M. (2018). Free Fatty Acid Receptor GPR40 Mediates Lipid Emulsion-induced Cardioprotection. Anesthesiology:129(1):154-162. doi: 10.1097/ALN.0000000000002195. PMCID: PMC6084795. Accompanied by news release. http://newsroom.ucla.edu/releases/study-identifies-receptor-that- may-be-targetedto-repair-the-heart-after-heart-attack-cardiac-arrest
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Umar S., Cunningham C.M., Itoh Y., Moazeni S., Vaillancourt M., Sarji S. Centala A., Arnold A.P. & Eghbali M. (2018). The Y Chromosome Plays a Protective Role in Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine: 197(7):952-955. doi: 10.1164/rccm.201707- 1345LE. PMID: 28934553. (Accompanied by Editorial, and Press Release).
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Cunningham C.M., Eghbali M. (2018). An Introduction to Epigenetics in Cardiovascular Development, Disease, and Sexualization. Adv Exp Med Biol:1065:31-47. doi: 10.1007/978-3-319-77932-4_2
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Saddic LA, Howard-Quijano K, Kipke J, Kubo Y, Dale EA, Hoover DB, Shivkumar K, Eghbali M, Mahajan A. (2018). Progression of myocardial ischemia leads to unique changes in immediate early gene expression in the spinal cord dorsal horn. Am J Physiol Heart Circ Physiol. doi: 10.1152/ajpheart.00337.2018. PMID: 30216122.
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Barske J., Eghbali M., Kosarussavadi S., Choi E., Schlinger B.A. (2018). The heart of an acrobatic bird. Comp Biochem Physiol A Mol Integr Physiol. pii: S1095-6433(18)30251-4. doi: 10.1016/j.cbpa.2018.10.010. PMID: 30367962.
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Iorga A., Umar S., Ruffenach G., Aryan L., Li J., Sharma S., Motayagheni N., Nadadur R.D., Bopassa J.C., Eghbali M. (2018). Estrogen rescues heart failure through estrogen receptor Beta activation. Biol Sex Differ;9(1):48. doi: 10.1186/s13293-018-0206-6. PMID: 30376877.
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Sulaiman D, Li J, Devarajan A, Cunningham CM, Li M, Fishbein GA, Fogelman AM, Eghbali M, Reddy ST. (2019). Paraoxonase 2 protects against acute myocardial ischemia-reperfusion injury by modulating mitochondrial function and oxidative stress via the PI3K/Akt/GSK-3β RISK pathway. J Mol Cell Cardiol;129:154-164. doi: 10.1016/j.yjmcc. PMID: 30802459.
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Umar S. & Eghbali M. (2019). In Reply. Free Fatty Acid Receptor GPR40 Mediates Lipid Emulsion- induced Cardioprotection. Anesthesiology;130(3):519-521. doi: 10.1097/ ALN. 0000000000002566. PMID: 30762648.
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Medzikovic L., Aryan L.& Eghbali M. (2019). Connecting sex-differences, estrogen signaling, and microRNAs in cardiac fibrosis. J Mol Med;97(10):1385-1398. doi: 10.1007/s00109-019-01833-6. PMID: 3144838.
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Ruffenach G., Umar S., Vaillancourt, M., Hong J., Cao N., Sarji S., Moazeni S., Cunningham C.M., Ardehali A., Reddy S.T., Saggar S., Fishbein G. & Eghbali M. (2019). Histological Hallmarks and Role of Slug/PIP Axis in Pulmonary Hypertension Secondary to Pulmonary Fibrosis. EMBO Mol Med; 11(9):e10061. doi: 10.15252/emmm.201810061. PMID: 31468711. Accompanied by news release http://newsroom.ucla.edu/releases/therapeutic-target-high-blood-pressure-lungs
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Mikhael M., Makar C., Wissa A., Le T., Eghbali M. & Umar S. (2019). Oxidative Stress and Its Implications in the Right Ventricular Remodeling Secondary to Pulmonary Hypertension. Front Physiol; 10: 1233. doi: 10.3389/fphys.2019.01233. PMCID: 6769067.
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Duhachek-Muggy S., Bhat K., Medina P., Cheng F., He L., Alli C., Saki M., Muthukrishnan S.D., Ruffenach G., Eghbali M., Vlashi E., Pajonk F. (2020). Radiation Mitigation of the Intestinal Acute Radiation Injury in Mice by 1-(4-Nitrophenyl)Sulfonyl-4-Phenylpiperazine. Stem Cells Transl Med;9(1):106-119. doi: 10.1002/sctm.19-0136. PMID: 31464098.
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Umar S., Ruffenach G., Moazeni S., Vaillancourt M., Hong J., Cunningham C.M., Cao N., Navab S., Sarji S., Li M., Lee L., Fishbein G., Ardehali A., Navab M., Reddy S.T. & Eghbali M. (2020). Involvement of Low-Density Lipoprotein Receptor in the Pathogenesis of Pulmonary Hypertension. J Am Heart Assoc;9(2):e012063. doi: 10.1161/JAHA.119.012063. PMID: 31914876.
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Aryan L., Medzikovic L., Umar S. & Eghbali M. (2020). Pregnancy-Associated Cardiac Dysfunction and the Regulatory Role of microRNAs. Biology of Sex Differenecs;11(1):14. doi: 10.1186/s13293-020- 00292-w. PMCID: PMC7137306
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Aryan L., Younessi D., Zargari M., Banerjee S., Agopian J., Rahman S., Borna R., Ruffenach G., Umar S. & Eghbali M. (2020). The Role of Estrogen Receptors in Cardiovascular Diseases. Int J Mol Sci;21(12):4314. doi: 10.3390/ijms21124314. PMCID: PMC7352426
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Ruffenach G., O’Connor E., Vaillancourt M., Jason Hong J., Cao N., Sarji S., Moazeni S., Papesh J., Grijalva V., Cunningham C.M., Shu L., Chattopadhyay A., Tiwari S., Mercier O., Perros F., Umar S., Yang X., Gomes A.V., Fogelman A., Reddy S.T. & Eghbali M. (2020). Oral 15-HETE Induces Pulmonary Hypertension in Mice by Triggering T-cell Dependent Endothelial Cell Apoptosis. Hypertension. 2020 Sep;76(3):985-996. doi: 10.1161/HYPERTENSIONAHA.120.14697. PMID: 32713273
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Medzikovic L., Cunningham C.M., Li M., Amjedi M., Hong J., Ruffenach G., Eghbali M. (2020). Sex differences underlying preexisting cardiovascular disease and cardiovascular injury in COVID-19. J Mol Cell Cardiol;2020 Nov:148:25-33. PMCID: PMC7442559.
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Lee LK, Medzikovic L, Eghbali M, Eltzschig HK, Yuan X. (2020). The Role of MicroRNAs in Acute Respiratory Distress Syndrome and Sepsis, From Targets to Therapies: A Narrative Review. Anesth Analg;2020 Nov;131(5):1471-1484. PMID: 33079870.
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Ruffenach G, Hong J, Vaillancourt M, Medzikovic L, Eghbali M. (2020). Pulmonary hypertension secondary to pulmonary fibrosis: clinical data, histopathology and molecular insights. Respir Res;2020 Nov; 21(1):303. PMID: 33208169.
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Nguyen TP, Frautschy SA, Eghbali M. (2021). Oxidative Stress in Myocardial and Neural Remodeling. Front Physiol;12:606484. doi: 10.3389/fphys.2021.606484. PMID: 33613307.
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Lee LK, Eghbali M, Sapru A. (2021). A novel miRNA biomarker panel associated with mortality in pediatric patients with ARDS. Respir Res;22(1):169. doi: 10.1186/s12931-021-01761-5. PMID: 34088312.
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Hong J, Arneson D, Umar S, Ruffenach G, Cunningham CM, Ahn IS, Diamante G, Bhetraratana M, Park JF, Said E, Huynh C, Le T, Medzikovic L, Humbert M, Soubrier F, Montani D, Girerd B, Trégouët DA, Channick R, Saggar R, Eghbali M*, Yang X.* (2021). Single-Cell Study of Two Rat Models of Pulmonary Arterial Hypertension Reveals Connections to Human Pathobiology and Drug Repositioning. Am J Respir Crit Care Med;203(8):1006-1022. doi: 10.1164/rccm.202006-2169OC. PMID: 33021809.*Co-Senior Author
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Yazal T, Bailleul J, Ruan Y, Sung D, Chu FI, Palomera D, Dao A, Sehgal A, Gurunathan V, Aryan L, Eghbali M, Vlashi E. (2022). Radiosensitizing Pancreatic Cancer via Effective Autophagy Inhibition. Mol Cancer Ther;21(1):79-88. doi: 10.1158/1535-7163.MCT-20-1103. PMID: 34725193.
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Jayawardena E, Medzikovic L, Ruffenach G, Eghbali M. (2022). Role of miRNA-1 and miRNA-21 in Acute Myocardial Ischemia-Reperfusion Injury and Their Potential as Therapeutic Strategy. Int J Mol Sci;23(3):1512. doi: 10.3390/ijms23031512. PMID: 35163436.
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Cunningham C. M., Li M., Ruffenach G., Doshi M., Aryan L., Hong J., Park J., Hrncir H., Medzikovic L., Umar S., Arnold A.P. & Eghbali M. (2022). Y-Chromosome gene, Uty, protects against pulmonary hypertension by reducing proinflammatory chemokines. American Journal of Respiratory and Critical Care Medicine;206(2):186-196. doi: 10.1164/rccm.202110-2309OC. PMID: 35504005. Accompanied by an editorial view and news release
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Sherman C, Koons N, Zargari M, Cha C, Hirsch J, Hong R, Eghbali M, Umar S. (2022). Intralipid Fails to Rescue Bupivacaine-induced Cardiotoxicity in Late Pregnant Rats. Frontiers of Medicine;9:899036. doi: 10.3389/fmed.2022.899036. PMID: 36035396; PMCID: PMC9411664.
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Ruffenach G., Medzikovic L., Aryan L., Li M. & Eghbali M. (2022). HNRNPA2B1: an RNA-binding protein that orchestrates smooth muscle cell phenotype in pulmonary arterial hypertension. Circulation ;101161CIRCULATIONAHA122059591. doi: 10.1161/CIRCULATIONAHA.122.059591. PMID: 35993245.
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Hong J., Wong B., Huynh C., Tang B., Ruffenach G., Li M., Umar S., Yang X., Eghbali M (2022). Tm4sf1- marked Endothelial Subpopulation Is Dysregulated in Pulmonary Arterial Hypertension. American Journal of Respiratory Cell and Molecular Biology: DOI: 10.1165/rcmb.2022-0020OC. PMID: 36252184.
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Banerjee S, Zargari M, Russino H, Medzikovic L, Mikhael M, Koons N, Grogan T, Rahman S, Eghbali M, Umar S. (2022). Acute Administration of Intralipid Improves Left Ventricular Function in Rats with Lipopolysaccharide-induced Endotoxemia via Src-STAT3 Mediated Mechanism. British Journal of Anesthesia; S0007-0912(22)00590-6. doi: 10.1016/j.bja.2022.10.019.
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Medzikovic L., Aryan L., Ruffenach G., Li M., Savalli N., Sun W., Sarji S., Hong J., Sharma S., Olcese R., Fishbein G., Eghbali M. (2023). Myocardial fibrosis and calcification are attenuated by microRNA- 129-5p targeting Asporin and Sox9 in cardiac fibroblasts. JCI Insight; 8(9):e168655. doi: 10.1172/jci.insight.168655. PMID: 37154157